About VacciCheck

VacciCheck® Panleukopenia Antibody Titer Kit is a simple and affordable in-clinic titer test designed to monitor serological status and immunization success to prevent over and under vaccination consequences.


Measures antibody titer to Panleukopenia, with reliable and accurate results in just 21 minutes!

About VacciCheck

ImmunoComb VacciCheck is:

  • The only semi-quantitative kit on the market
  • Solid phase “dot” ELISA
  • Affordable and simple to run
  • A guide for revaccination decisions
  • Self contained
  • Shelf life of 9 months – 1 year
  • Results in just 21 minutes

Serology testing is useful after a vaccination to determine antibody levels for Panleukopenia. In this way the veterinarian can modify vaccine programs for individual kittens. The cut-off values of the VacciCheck kits correlate with the vaccination recommendations of the Cornell University School of Veterinary Medicine.

Two main components:

The comb has 12 teeth. Each tooth tests one blood or serum sample and will provide results in the form of developed grey dots


The developing plate has multiple compartments, which contain the necessary reagents for comb developments.

Obtaining Results

1. Obtain blood or serum from animal(s). Just 5 µL serum or 10 µL blood.
2. Deposit blood or serum sample(s) into well(s) A in developing plate.
3. Insert Comb into well(s) A. Incubate for specified time.
4. Transfer the Comb from well(s) A to well(s) F in a timed sequence. Time intervals vary according to type of kit.
5. Let Comb dry and read results. The color intensity of spots on Comb corresponds to antibody level.


AAFP Feline Vaccination Advisory Panel Report

The American Association of Feline Practitioners 2013 report on feline vaccination protocols and how they should be followed in your practice.

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Disease Information: Panleukopenia

This Disease Information Fact Sheet accompanies the 2013 AAFP Feline Vaccination Advisory Panel Report published in the Journal of Feline Medicine and Surgery.

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Evaluation of an in-house dot enzyme-linked immunosorbent assay to detect antibodies against feline panleukopenia virus

Published in Journal of Feline Medicine and Surgery, by Katherina Mende1, Bianca Stuetzer1, Uwe Truyen, and Katrin Hartmann

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Performance Report: ImmunoComb Feline Panleukopenia Virus Antibody Test Kit

A field trial to assess the performance of the ImmunoComb Feline Panleukopenia Virus Antibody Test Kit was done in comparison to the gold standard Hemagglutination Inhibition (HI) assays.

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Titer Testing: Making Vaccinations More Scientific

Featured in Dogs Naturally Magazine, Catherine O’Driscoll, founder of Pet Welfare Alliance, an organization that brings together animal advocates and pet owners from around the world, discusses VacciCheck and the benefits of titer testing rather than immediate vacciantion.

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Sensitivity Specificity

Sensitivity, specificity, accuracy and difference between positive and negative mean results of the ImmunoComb® VacciCheck Antibody Test Kit. (2009) Mazar S.1, Larson L.2 and Lavi Y.31

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Find Out Why Once Every Three Years is the Trend in Vaccinations

Veterinary Practice News article: When did the shift away from the annual vax start? By Don Jergler

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Considerations for the Titer Testing

A report by Ronald D. Schultz, PhD, Dipl. ACVIM, Professor and Chair, Department of Pathobiological Sciences School of Veterinary Medicine – University of Wisconsin-Madison

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The Outdated Vet Vaccination Advice That Can Harm Your Pet

Dr. Karen Becker looks into why 60% of vets are still doing annual re-vaccination despite the now 2-year old guidelines that contradict this practice.

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Incorporating Titer Testing in Your Practice

A report by Shawn Messonnier, DVM on how he has successfully implement titer testing in his practice with the use of VacciCheck.

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Vital Vaccination Series: Antibody Titers Versus Vaccination

A peer reviewed report by Richard B. Ford, DVM, MS, Diplomate ACVIM & ACVPM (Hon) on the benefits of titer testing with the availability of in clinic tests like VacciCheck.

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What We Need to Know About Vaccinations and Titer Testing

A report by Professor Michael J. Day, BSc BVMS(Hons) PhD DSc DiplECVP FASM FRCPath FRCVS, School of Veterinary Sciences, University of Bristol

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Co-Parenting Your Pet

A featured article in Dogs Today May 2012 edition by Richard Allport who runs a large referral center in Hertfordshire, offering a range of natural therapies for pets, including homeopathy, herbal medicine, acupuncture and healing.

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New guidelines address over-vaccination issue

The Chicago Tribune’s My Pet World by Steve Dale looks at the potential dangers, and risks associated with over-vaccination in animals. Several controversial issues are discussed in the 2011 American Animal Hospital Association (AAHA) Vaccination Guidelines.

View Article [PDF]

Video & Radio

Video & Radio Library

Video Library:

Reviewing Vital Vaccinations
Dr. Richard Ford, DVM, MS, DACVIM, DACVPM speaks at the 2015 NAVC to a large audience about the vital vaccination series and importance of titer testing.

Running Canine VacciCheck Test
Dr. Ron Schultz, Professor and Chair of the Department of Pathobiological Sciences at the University of Wisconsin School of Veterinary Medicine and his assistant Bliss Thiel demonstrate how to run the Canine VacciCheck antibody test. Brought to you by Maddie’s Fund.

Antibody Titer Tests
Dr. Annette Litster, Director of Maddie’s Shelter Medicine Program at Purdue University, talks about the use of antibody titer tests in animal shelters. Brought to you by Maddie’s Fund.

Interpreting Canine VacciCheck Test
Dr. Ron Schultz, Professor and Chair of the Department of Pathobiological Sciences at the University of Wisconsin School of Veterinary Medicine and his assistant Bliss Thiel demonstrate how to interpret the Canine VacciCheck antibody results. Brought to you by Maddie’s Fund.

Everything You Need to Know about Using VacciCheck
VacciCheck manufacturer Biogal Galed goes over everything you need to know about using their ImmunoComb product to obtain quick and easy titer results in just 21 minutes!

Vaccinosis Webinar 3/18/14 – Dr. Patrick Mahaney MVD
Interactive webinar from March 18, 2014 with Dr. Patrick Mahaney MVD. We discuss the various ways in which he has been able to successfully implement titer testing into his practice to avoid Vaccinosis and other dangerous side effects of over and under vaccination. Learn when titer testing is appropriate, why it is necessary, and how you can make it standard practice in your clinic.

Radio Appearances:

Pet Parents’ Action Group (04-05-2012) Catherine O’Driscoll on the BBC Radio London ‘Barking at the moon’ show interviews Lenny Small of Biogal, the company behind VacciCheck. Listen here: 


PAWS Radio Vet Pet (09-01-2013) Our very own Lyndee Kelver joins Dr. Randy for PAWS Radio Vet Pet to talk about VacciCheck and callers share their own personal experiences with vaccinations. Listen below or click here to visit PAWS Radio Vet Pet online.

Cat Chat® & Dog Talk® (05-28-2013) The Vaccicheck show! Dr. Ron Schulz calls to explain about the deadly CORE diseases, why puppy shots are so vital and why the blood titer test Vaccicheck is so valuable for puppies and geriatric dogs — like Rebecca’s, who calls from SO. California about whether to vaccinate her aging pooch with a foot tumor. Listen below or click here for more from the Radio Pet Lady Network.